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Scientist offers clues in mystery hepatitis outbreak in children

A British scientist investigating a mysterious global hepatitis outbreak that has infected hundreds of children globally believes researchers are getting closer to identifying its cause as more clues begin to emerge.



Judith Breuer, professor of virology and director of the pathogen genomics unit at University College London, was approached by the UK Health Security Agency to investigate a cluster of cases detected in Scotland last month.


She and a research team at Great Ormond Street Hospital in London are using metagenomics, the study of genetic material, to analyse which viruses are present in the RNA and DNA samples belonging to affected children in the hope it can offer insight into the source of the outbreak.

Although firm conclusions have yet to be made, adenovirus and immune systems weakened by coronavirus lockdowns are thought to be key factors.


What do we know so far?


At least 348 children around the world have been diagnosed with this new hepatitis, with some being forced to undergo liver transplants and some countries, such as Ireland and Indonesia, reporting a small number of deaths.


As of May 12, the HSA reported 176 confirmed cases of sudden onset hepatitis in under-10s in Britain. At least 11 of those have had liver transplants.


The cases are predominantly in children under 5, who showed initial symptoms of gastroenteritis, including diarrhoea and nausea, followed by the onset of jaundice.


None of the usual viruses that cause hepatitis (hepatitis viruses A to E) have been found in the children who have suffered from the recent cases.


Read More : https://www.thenationalnews.com/health/2022/05/17/scientist-offers-clues-in-mystery-hepatitis-outbreak-in-children/

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